We offer compounded Semaglutide featuring the same active ingredient as the commercial product Wegovy®
Disclaimer: Compounded medications are not FDA-approved and should be discussed with your healthcare provider to understand the specific risks and benefits. While compounded in licensed pharmacies, these medications may not have the same safety and efficacy profiles as commercially available drugs.
Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist that has shown remarkable effectiveness in promoting weight loss. It works by regulating appetite and food intake, leading to significant and sustained weight reduction.
Mechanism of Action: Semaglutide mimics the GLP-1 hormone, which is crucial for appetite control. It works by:
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Enhancing insulin secretion in response to meals
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Suppressing glucagon release, which reduces hepatic glucose production
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Slowing gastric emptying, leading to prolonged satiety and reduced appetite
These combined effects help reduce calorie intake and promote weight loss.
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Semaglutide’s efficacy in weight loss has been demonstrated in several clinical trials, particularly the STEP trials:
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STEP 1:
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Participants: Individuals with a BMI ≥30 or ≥27 with at least one weight-related comorbidity (excluding diabetes).
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Results: Participants receiving Semaglutide 2.4 mg once weekly lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group.
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STEP 2:
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Participants: Individuals with type 2 diabetes and a BMI ≥27.
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Results: Participants receiving Semaglutide 2.4 mg once weekly lost an average of 9.6% of their body weight over 68 weeks, compared to 3.4% in the placebo group.
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STEP 3 and 4:
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These trials further confirmed the efficacy of Semaglutide in weight management, showing significant weight reductions and improvements in cardiometabolic risk factors.
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Safety Profile: Semaglutide is generally well-tolerated, with the most common side effects being gastrointestinal, such as nausea, vomiting, diarrhea, and constipation. These symptoms are usually mild to moderate and tend to decrease over time. Serious but rare side effects may include pancreatitis, gallbladder issues, and kidney problems.
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Administration: Semaglutide is administered as a subcutaneous injection once a week. It can be injected into the abdomen, thigh, or upper arm. Proper injection technique and schedule should be followed as instructed by a healthcare provider.
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Semaglutide is a highly effective medication for weight management, with substantial clinical evidence supporting its ability to achieve significant and sustained weight loss. It offers a promising option for individuals struggling with obesity or overweight with weight-related comorbidities. Discuss with your healthcare provider to determine if Semaglutide is right for you and to understand the potential risks and benefits.